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Different imaging characteristics between unilateral and bilateral polypoidal choroidal vasculopathy
1Department of Ophthalmology, First Hospital of China Medical University, Shenyang, People's Republic of China.
Photodiagnosis and Photodynamic Therapy
|February 10, 2019
Summary
Imaging characteristics differ between unilateral and bilateral polypoidal choroidal vasculopathy (PCV). Subfoveal choroidal thickness, ICGA hyperfluorescent spots, and drusen presence distinguish these PCV presentations.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Diseases
Background:
- Polypoidal choroidal vasculopathy (PCV) is a subtype of neovascular age-related macular degeneration.
- Understanding imaging differences between unilateral and bilateral PCV is crucial for diagnosis and management.
Purpose of the Study:
- To compare imaging characteristics of unilateral versus bilateral polypoidal choroidal vasculopathy (PCV).
- To identify key features differentiating these two presentations using advanced imaging modalities.
Main Methods:
- Retrospective case series involving 53 patients with PCV.
- Diagnostic indocyanine green angiography (ICGA) and spectral domain optical coherence tomography (SD-OCT) were utilized.
- Confocal scanning laser ophthalmoscope assessment was performed.
Main Results:
- Bilateral PCV cases exhibited significantly lower subfoveal choroidal thickness (SFCT) compared to unilateral cases and their fellow eyes.
- ICGA hyperfluorescent spots correlated positively with SFCT in unilateral PCV eyes but not in bilateral cases.
- Drusen were more prevalent in fellow eyes of the unilateral PCV group.
Conclusions:
- Subfoveal choroidal thickness (SFCT), ICGA hyperfluorescent spots, and drusen presence are key imaging differentiators between unilateral and bilateral PCV.
- These findings aid in distinguishing PCV presentations and may inform treatment strategies.
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