Intravenous leiomyomatosis with different surgical approaches: Three case reports
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Updated: Jan 29, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Jie He1, Zheng-Bo Chen2, San-Ming Wang2
1Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong Province, China.
Insights
Intravenous leiomyomatosis (IVL) is a rare condition requiring surgery. Optimal surgical approach depends on patient condition and tumor extent, necessitating thorough preoperative evaluation.
Area of Science:
- Cardiovascular Surgery
- Gynecologic Oncology
- Vascular Surgery
Background:
- Intravenous leiomyomatosis (IVL) is a rare neoplastic proliferation of smooth muscle cells.
- Surgical management of IVL is complex and requires a multidisciplinary team approach.
- Optimal surgical strategies for IVL remain undetermined.
Observation:
- This report details three cases of IVL managed with distinct surgical techniques.
- Patients presented with circulatory compromise, including lower extremity edema and palpitations.
- Diagnosis was confirmed via imaging and histopathological examination.
Findings:
- All three patients successfully underwent surgical resection of IVL.
- Postoperative recovery was uneventful, with no reported complications.
- Surgical outcomes were favorable across different approaches.
Implications:
- Comprehensive preoperative assessment is vital for effective IVL surgical planning.
- The choice of surgical approach should be tailored to individual patient circumstances and tumor characteristics.
- Further research into standardized surgical protocols for IVL is warranted.
Background:
Intravenous leiomyomatosis (IVL) is a rare and complicated disease, which requires surgery by a multidisciplinary team. However, the optimal surgical approach has not been determined.
Case Summary:
Here we report three cases of IVL treated with different surgical approaches. All patients presented with circulation symptoms. Two patients had lower extremity edema and the other had cardiopalmus. The diagnosis of IVL was confirmed based on the imagining examinations and pathological findings. All patients underwent surgical treatment and were discharged without any complications.
Conclusion:
Preoperative examination is crucial for surgical planning and surgical approach is dependent on the patient's condition and tumor involvement.
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