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Central Venous Sinus Thrombosis in a Boy With Acute Severe Ulcerative Colitis

Rafael Martín-Masot1, Pilar Ortiz Pérez1, Juliana Serrano Nieto1

  • 1Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, Málaga, Spain.

Frontiers in Pediatrics
|February 19, 2019
PubMed

Insights

Cerebral venous sinus thrombosis (CVST) is rare in children and can be linked to inflammatory bowel disease (IBD). This case highlights the potential benefit of prophylactic anticoagulation in pediatric IBD patients, particularly after surgery.

Area of Science:

  • Pediatric Gastroenterology
  • Pediatric Neurology
  • Hematology

Background:

  • Cerebral venous sinus thrombosis (CVST) is an uncommon but serious condition in children.
  • Inflammatory bowel disease (IBD), specifically ulcerative colitis, is an established risk factor for thrombosis.
  • Thrombosis is recognized as an extraintestinal manifestation of IBD.

Observation:

  • A 5-year-old child with ulcerative colitis developed transverse sinus thrombosis shortly after undergoing a colectomy.
  • The patient's presentation occurred in the context of evolving recommendations regarding thromboprophylaxis in pediatric IBD.

Findings:

  • The case underscores the potential for CVST in pediatric IBD patients, even with prophylaxis considerations.
  • Immediate post-colectomy transverse sinus thrombosis in a pediatric ulcerative colitis patient is a critical observation.

Implications:

  • This case supports the consideration of prophylactic anticoagulation, such as low-molecular-weight heparin, in pediatric IBD patients at risk for thrombosis.
  • Increased awareness of these recommendations and the potential benefits of prophylaxis is crucial for managing pediatric IBD patients.
  • Further research and discussion are warranted to clarify the controversial topic of thromboprophylaxis in this population.

Keywords:
cerebral venous sinus thrombosis (CVST)cerebral venous thrombosis (CVT)inflammatory bowel diseasepediatricsprophylaxis

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