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Published on: December 6, 2016
Surgery for Obstructive Sleep Apnea in Obese Children: Literature Review and Meta-analysis
Patrick Scheffler1, Nikolaus E Wolter1, Indra Narang2
11 Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Insights
Surgical treatments for obstructive sleep apnea (OSA) in obese children improve key metrics but have high persistent OSA rates. Patient selection and weight management are crucial for better outcomes in this population.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Bariatric Surgery
Background:
- Obstructive sleep apnea (OSA) significantly impacts overweight and obese children's health.
- Surgical interventions for OSA in this population may have variable efficacy compared to normal-weight children.
Purpose of the Study:
- To systematically review and meta-analyze the effectiveness of surgical interventions for OSA in obese children.
- To compare the outcomes of different surgical procedures for pediatric OSA in overweight and obese populations.
Main Methods:
- A systematic literature search was conducted across PubMed, Ovid, and Cochrane databases.
- Studies on adenotonsillectomy, uvulopalatopharyngoplasty, supraglottoplasty, and tongue base surgeries were included.
- Adenotonsillectomy data underwent meta-analysis using a random-effects model based on polysomnographic findings.
Main Results:
- Adenotonsillectomy significantly improved apnea-hypopnea index and respiratory disturbance index, but persistent OSA rates ranged from 51% to 66%.
- Uvulopalatoplasty showed limited effectiveness (12.5%), while tongue base surgery had higher persistent OSA rates (74%-88%).
- Surgical interventions reduce OSA severity but demonstrate higher persistent OSA rates in obese children.
Conclusions:
- Surgical interventions for pediatric OSA in overweight and obese children effectively reduce OSA severity but are associated with higher persistent OSA rates.
- The effectiveness varies by surgical procedure, highlighting the need for careful patient selection and preoperative weight management.
- Setting realistic postoperative expectations for parents is essential for this challenging patient group.
Objectives:
Surgical intervention for obstructive sleep apnea (OSA) in overweight and obese children may not be as effective as it is in normal-weight children. The purpose of this study was to systematically review the effects of various surgical interventions for OSA in obese children and to meta-analyze the current data.
Data Sources:
PubMed, OVID, and Cochrane databases.
Review Methods:
Databases were searched for studies examining adenotonsillectomy, uvulopalatopharyngoplasty, supraglottoplasty, or tongue base surgeries and combinations in obese children with OSA. Adenotonsillectomy was the only procedure with enough data for meta-analysis; polysomnographic data were extracted and analyzed using a random-effects model.
Results:
For adenotonsillectomy, 11 studies were included in the meta-analysis. Despite significant improvement in the apnea-hypopnea index (22.9 to 8.1 events/h, P < .001), respiratory disturbance index (24.8 to 10.4 events/h, P < .001), and oxygen saturation nadir (78.4% to 87.0%, P < .001), rates of persistent OSA ranged from 51% to 66%, depending on the outcome criterion used. There was evidence of limited effectiveness for surgical interventions to treat OSA in obese children using uvulopalatoplasty (12.5%) and tongue base surgery (74%-88%).
Conclusions:
Surgical interventions for OSA in overweight and obese children are effective at reducing OSA but with higher rates of persistent OSA than reported for normal-weight children. However, the amount of reduction appears to vary by surgical procedure. More attention should be paid toward preoperative weight loss and patient selection, and parents should be provided with realistic postoperative expectations in this difficult-to-treat population.
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