Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Maksymilian Brzezicki1, Matthew Kobetic2, Dillon Serena3

  • 1Bristol Institute of Clinical Neurosciences, Southmead Hospital; University of Oxford Nuffield Department of Clinical Neurosciences.

Fortschritte Der Neurologie-Psychiatrie
|February 26, 2019
PubMed
Summary

This case study details central nervous system vasculitis with a relapsing-remitting course and unique cognitive deficits. It highlights diagnostic challenges and potential therapeutic roles for statins in managing this rare neurological condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A systematic review of clinical outcome reporting for curative surgical treatment of patients with pancreatic adenocarcinoma.

HPB : the official journal of the International Hepato Pancreato Biliary Association·2025
Same author

Development of a core data set for describing, measuring and reporting the learning curve in studies of novel invasive procedures: study protocol.

BMJ open·2024
Same author

Shared Learning Utilizing Digital Methods in Surgery to Enhance Transparency in Surgical Innovation: Protocol for a Scoping Review.

JMIR research protocols·2022
See all related articles

Area of Science:

  • Neurology
  • Immunology
  • Vascular Medicine

Background:

  • Central nervous system vasculitis (CNSV) is a rare condition characterized by inflammation of blood vessels in the brain and spinal cord.
  • It can present with diverse neurological symptoms, often mimicking other neurological disorders, posing diagnostic challenges.
  • A relapsing-remitting course is uncommon but has been reported in specific variants of CNSV.

Observation:

  • A patient presented with a recurrent pattern of bilateral headache, visual disturbances (hemianopsia, dyschromatopsia), and transient loss of consciousness over eight years.
  • Magnetic Resonance (MR) imaging revealed bilateral, non-specific hyperintensities suggestive of vascular origin.
  • The patient experienced periods of complete remission lasting 4-6 months between symptomatic episodes.

Findings:

Related Experiment Videos

  • The case illustrates a unique presentation of CNSV with a distinct relapsing-remitting pattern.
  • Uncommon cognitive deficits were observed, adding to the complexity of the clinical presentation.
  • The findings underscore the diagnostic difficulties in identifying CNSV, especially with atypical features.

Implications:

  • This case expands the understanding of clinical manifestations and disease course in central nervous system vasculitis.
  • It emphasizes the need for a high index of suspicion for CNSV in patients with unexplained recurrent neurological symptoms.
  • The report prompts further investigation into the potential role of statins in managing CNSV, particularly in cases with specific lipid profiles or inflammatory markers.