[Clinical analysis of 54 patients with non-syndromic enlarged vestibular aqueduct]

Objective:To further recognize the clinical characteristics of non-syndromic enlarged vestibular aqueduct through the retrospective analysis of cases, with the purpose of providing references for clinical diagnosis and treatment. Method:Collect 54 cases of non-syndromic enlarged vestibular aqueduct, and analyze their clinical characteristics after history taking, physical examination, audiometry and imaging examination. Measure the biggest width of midpoint between internal and external of vestibular aqueduct on temporal bone thin-section CT, and analyze the relationship between the pipe width and sides of ear, types of hearing loss and degree of hearing loss through t test. Result:All 54 patients with non-syndromic enlarged vestibular aqueduct had bilateral ear involvement. There were 42 cases with prelingual deafness, 12 cases with postlingual deafness, and there were 38 ears with severe deafness, 70 ears with profound deafness. Ninety-six ears of hearing loss showed sensorineural deafness, and 12 ears manifested mixed deafness. The biggest width of midpoint between internal and external of vestibular aqueduct spread over 1.60-3.90 mm, and the average was 2.60 mm. There were no significant differences in data between left and right sides, degree of hearing loss and type of hearing loss. Conclusion:Non-syndromic enlarged vestibular aqueduct mainly manifests serious sensorineural deafness, and the diagnosis depends on imaging examination. There is no difference in the degree of expanding between left and right ear, and the extent of enlargement is not related to the type and the severity of hearing loss.