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Updated: Jan 28, 2026
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Cutaneous Surgical Denervation: A Method for Testing the Requirement for Nerves in Mouse Models of Skin Disease
Published on: June 26, 2016
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Assessing Skin Biopsy Rates for Histologic Findings Indicative of Nonpathological Cutaneous Disease.
James A Solomon1,2,3,4, Michael Oswalt1,2, Michael Nodzenski5
1Advanced Dermatology Cosmetic Surgery, Maitland, Florida.
Summary
The rate of skin biopsies for non-pathological skin conditions is not increasing. However, overall skin biopsy rates per visit have risen due to increased detection of pathological skin diseases.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Skin biopsies have increased, potentially linked to a rise in skin cancer.
- This trend may be preventable, offering opportunities for cost savings.
Purpose of the Study:
- To investigate if the rise in skin biopsies is due to an increase in biopsies for non-pathological skin conditions.
- Define pathological cutaneous disease as malignancy, precancerous lesions, or conditions impacting quality of life.
Main Methods:
- Retrospective cohort study from 2006-2013.
- Analysis of consecutive skin biopsy data from a dermatology practice in Florida and Ohio.
- Examined 267,706 skin biopsies performed by an average of 52 providers monthly.
Main Results:
- Biopsy rates per visit increased by 2% annually.
- The likelihood of biopsies for non-pathological skin conditions did not significantly increase over time (OR: 0.99).
Conclusions:
- The increase in skin biopsies is not driven by non-pathological conditions.
- Rising biopsy rates are likely due to improved detection of pathological dermatologic diseases.
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