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Updated: Jan 28, 2026

Isolation of Functional Cardiac Immune Cells
Published on: December 5, 2011
[Diagnosis of isolated cardiac sarcoidosis]
E L Trisvetova1, O A Yudina2, A Z Smolensky3
1Belarusian State Medical University, Minsk, Republic of Belarus.
Abstract:
Heart involvement in sarcoidosis is diagnosed in vivo in 5-7%, at autopsy in 25% of cases as a manifestation of a systemic process and an isolated one. Difficulties in the diagnosis of isolated sarcoidosis are due to the absence of known causes of the disease and to the lack of specificity of clinical manifestations. The main symptoms include cardiac conduction and rhythm disturbances, cardiomyopathy with the development of heart failure, as well as pericardial involvement. Routine techniques (ECG, EchoCG, daily ECG monitoring) and imaging of the structures of the heart and its function evaluation (MRI, PET, and scintigraphy) are used in diagnosis. A set of clinical, instrumental, and histological data obtained at endomyocardial biopsy may suggest isolated cardiac sarcoidosis with the exception of other diseases.
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