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Successful Endoscopic Reduction of an Ileocolonic Intussusception in an Adult With Peutz-Jeghers Syndrome

Mohd Amer AlSamman1, Jason D Ferreira2, Abdelmoniem Moustafa1

  • 1The Warren Alpert Medical School of Brown University, The Miriam Hospital, Providence, RI, USA.

Gastroenterology Research
|March 6, 2019
PubMed

Insights

Peutz-Jeghers syndrome (PJS) can cause intestinal intussusception in adults, often requiring surgery. This case demonstrates successful endoscopic treatment for PJS-related intussusception in an adult, avoiding surgical intervention.

Area of Science:

  • Gastroenterology
  • Genetics
  • Surgical Oncology

Background:

  • Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder.
  • PJS is characterized by hamartomatous polyps in the gastrointestinal tract.
  • PJS commonly leads to gastrointestinal bleeding and obstructions.

Observation:

  • Intussusception is a rare complication of PJS in adults.
  • Most reported adult PJS intussusception cases necessitate surgical resection.
  • This report details a PJS-related intussusception in an adult patient.

Findings:

  • The adult patient with PJS-related intussusception was successfully treated.
  • Endoscopic treatment was employed, avoiding surgical intervention.
  • This case highlights a non-surgical approach for PJS intussusception.

Implications:

  • Endoscopic treatment is a viable alternative to surgery for adult PJS intussusception.
  • This approach may reduce morbidity associated with surgical resection in PJS patients.
  • Further research into endoscopic management of PJS complications is warranted.

Keywords:
EndoscopyIntussusceptionPeutz-Jeghers syndrome

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