Related Experiment Video
Updated: Jan 28, 2026

Author Spotlight: Development and Challenges of Feeding Assays for Insect Pest Management
Published on: May 26, 2023
Phytochemical and antitumor studies on Cynanchum mongolicum (Maxim.) Kom
Yong-Cheng Yang1, Yan-Ming Wang1, Zi-Jian Rong1
1School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.
Abstract:
A chemical investigation of Cynanchum mongolicum (Maxim.) Kom. identified 8 compounds. On the basis of spectroscopic data, they were determined to be 3 alkaloids and 5 sinapoyl esters, among which were two previously undescribed compounds (1 and 2). The inhibitory effects of the isolated compounds against four human tumor cell lines were evaluated in vitro by MTT assays, which revealed moderate inhibitory effects with IC50 values < 50 mM, in particularly, three antofine analogues have showed significant antitumor activities with IC50 values < 0.1 mM, which was obviously better than the 5-fluorouracil and potential to be used as cancer drugs.
Related Concept Videos
Case Studies
Imaging Studies I: Kidney, Ureter, and Bladder Studies
Longitudinal Studies
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Studying the Cytoskeleton
Bioavailability Study Design: Single Versus Multiple Dose Studies

