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Updated: Jan 28, 2026

Quantifying X-Ray Fluorescence Data Using MAPS
Published on: February 17, 2018
Scanning transmission X-ray microscopy with efficient X-ray fluorescence detection (STXM-XRF) for biomedical
Lars Lühl1, Konstantin Andrianov2, Hanna Dierks1
1Institute of Optics and Atomic Physics, Technische Universität Berlin, Hardenbergstraße 36, Berlin 10623, Germany.
Abstract:
Scanning transmission X-ray microscopy, especially in combination with X-ray fluorescence detection (STXM-XRF) in the soft X-ray energy range, is becoming an increasingly important tool for life sciences. Using X-ray fluorescence detection, the study of biochemical mechanisms becomes accessible. As biological matrices generally have a low fluorescence yield and thus a low fluorescence signal, high detector efficiency (e.g. large solid angle) is indispensable for avoiding long measurement times and radiation damage. Here, the new AnImaX STXM-XRF microscope equipped with a large solid angle of detection enabling fast scans and the first proof-of-principle measurements on biomedical samples are described. In addition, characterization measurements for future quantitative elemental imaging are presented.
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