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Updated: Jan 27, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
The calculus of preloading antiplatelet agents in ST-elevation myocardial infarction: Does it make a difference?
Arnold H Seto1, Morton J Kern1
1Medicine, VA Long Beach Healthcare System, Long Beach, California.
Abstract:
There is limited evidence supporting the preloading of potent oral P2Y12 inhibitors in ST-elevation myocardial infarction (STEMI). This study demonstrates that longer pretreatment times were associated with improved angiographic coronary flow grades and ST-segment resolution. Although larger studies would be needed to prove a clinical benefit, in the absence of harm preloading in STEMI would be the most reasonable strategy.
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