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Whey protein concentrate limits venous thrombosis in rats
Anna Tokajuk1, Agnieszka Zakrzeska2,3, Ewa Chabielska2
1a Department of Experimental Pharmacology, Medical University of Białystok, Szpitalna Str. 37, 15-295 Białystok, Poland.
Abstract:
To study the influence of whey protein concentrate (WPC-80) on the development of thrombosis, rats were supplemented with 2 doses of WPC-80 (0.3 or 0.5 g/kg) for 7, 14, or 21 days. Then, a 1-h venous thrombosis model was performed in half of the animals. Coagulation parameters, platelet count, and thrombus weight were assessed. Thrombus weight was decreased in rats obtaining WPC-80 and that was significant only for 14- and 21-day supplementation. There were slight differences between groups in coagulation parameters and platelet count but without evident direction. Further research is needed to clarify the observed effects.
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