Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

1.4K
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
1.4K
The Significance of Membrane Transport01:44

The Significance of Membrane Transport

41.5K
The transport of solutes across the cell membrane is essential for metabolic processes, like maintaining cell size and volume, generating the action potential, exchanging nutrients and gases, etc. Membrane transport can be either passive or active. It can be simple diffusion, facilitated, or mediated transport aided by transport proteins such as transporters and channels.
Transporters facilitate either an active or passive movement of solutes. They can allow a single-molecule transport down its...
41.5K
Significance of Center of Mass01:12

Significance of Center of Mass

7.7K
The center of mass of an object is defined as the mass-weighted average position of all the particles that comprise the object. The significance of the center of mass of an object can be seen by looking at its dynamics. The time derivative of the center of mass gives its velocity, assuming that the object's mass remains constant over time. Furthermore, the total linear momentum of an object can be seen as the linear momentum of a single particle of the object's total mass moving with...
7.7K
Statistical Significance01:50

Statistical Significance

21.3K
Once data is collected from both the experimental and the control groups, a statistical analysis is conducted to find out if there are meaningful differences between the two groups. A statistical analysis determines how likely any difference found is due to chance (and thus not meaningful). In psychology, group differences are considered meaningful, or significant, if the odds that these differences occurred by chance alone are 5 percent or less. Stated another way, if we repeated this...
21.3K
Physiological Pharmacokinetic Models: Assumption with Protein Binding01:13

Physiological Pharmacokinetic Models: Assumption with Protein Binding

247
Physiological models with protein binding in pharmacokinetics offer a sophisticated approach to understanding drug disposition. These models consider drug-protein interactions, enabling them to effectively predict drug concentrations in different organs and tissues. This precision aids in accurate drug dosing, providing a significant advantage over conventional models. A key process within these models is equilibration, which ensures that drug concentrations achieve a steady state within the...
247
Classifying Matter by Composition03:35

Classifying Matter by Composition

90.1K
Matter: Pure Substances and Mixtures
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures. 
A pure substance is a form of matter that has a constant composition throughout with uniform properties. For example, any sample of sucrose has the same composition and same physical properties, such as melting point, color, and sweetness, regardless of the source from which it is isolated. 
A mixture is composed of two or...
90.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Bifidobacteria infantis</i> and human milk oligosaccharides have independent and synergistic effects on immune response and amino acid metabolism in germ-free mouse models.

mSystems·2026
Same author

Enteral iron dose effect on iron storage, intestinal barrier, and gut microbiome in preterm infants: a randomized clinical trial.

The American journal of clinical nutrition·2026
Same author

Effects of Human Lactoferrin (Effera<sup>®</sup>) at Two Doses Versus Bovine Lactoferrin on the Adult Gut Microbiome and Fecal Short-Chain Fatty Acids: a Randomized, Double-Blind Trial.

Journal of dietary supplements·2026
Same author

Corrigendum to 'Western, Healthful, and Low-Preparation Diet Patterns in Preschoolers of the STRONG Kids2 Program' [Journal of Nutrition Education and Behavior 56/4 (2024) 219-229].

Journal of nutrition education and behavior·2026
Same author

Human Milk Oligosaccharides Support Coordinated Microbiome and Immune Development and Function in Infancy.

Annals of nutrition & metabolism·2026
Same author

Charting a New Era to Modernize United States Infant Formula Regulation.

Advances in nutrition (Bethesda, Md.)·2026

Related Experiment Video

Updated: Jan 27, 2026

Milk Collection in the Rat Using Capillary Tubes and Estimation of Milk Fat Content by Creamatocrit
07:38

Milk Collection in the Rat Using Capillary Tubes and Estimation of Milk Fat Content by Creamatocrit

Published on: December 16, 2015

13.1K

Human Milk Proteins: Composition and Physiological Significance.

Sharon M Donovan

    Nestle Nutrition Institute Workshop Series
    |March 14, 2019
    PubMed
    Summary

    Human milk (HM) proteins offer numerous benefits, including immune defense and gut health. Research reviews HM protein composition and bioactivity, with potential applications in infant formula.

    Area of Science:

    • Human Milk Proteins
    • Bioactive Peptides
    • Nutritional Biochemistry

    Background:

    • Human milk (HM) proteins are crucial for infant development, providing amino acids and immune support.
    • HM proteins have diverse functions: nutrient bioavailability, immunologic defense, gut maturation, microbiome modulation, and cognitive enhancement.
    • HM proteins are classified as caseins, whey proteins, and mucins, with whey predominant in early lactation.

    Purpose of the Study:

    • To review the current evidence on human milk protein composition.
    • To explore the bioactivity and functional properties of human milk proteins.
    • To discuss the potential applications of isolated milk proteins in infant nutrition.

    Main Methods:

    • Literature review of scientific evidence on human milk protein composition and function.

    More Related Videos

    A Method for Targeted 16S Sequencing of Human Milk Samples
    09:09

    A Method for Targeted 16S Sequencing of Human Milk Samples

    Published on: March 23, 2018

    10.3K
    Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles
    04:35

    Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles

    Published on: November 14, 2025

    359

    Related Experiment Videos

    Last Updated: Jan 27, 2026

    Milk Collection in the Rat Using Capillary Tubes and Estimation of Milk Fat Content by Creamatocrit
    07:38

    Milk Collection in the Rat Using Capillary Tubes and Estimation of Milk Fat Content by Creamatocrit

    Published on: December 16, 2015

    13.1K
    A Method for Targeted 16S Sequencing of Human Milk Samples
    09:09

    A Method for Targeted 16S Sequencing of Human Milk Samples

    Published on: March 23, 2018

    10.3K
    Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles
    04:35

    Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles

    Published on: November 14, 2025

    359
  • Analysis of protein classifications (caseins, whey, mucins) and their proportions.
  • Examination of recent advancements in dairy technology for protein isolation.

    • Main Results:

    • Human milk contains hundreds of proteins with varied functions, contributing to infant health.
    • Key whey proteins include α-lactalbumin, lactoferrin, IgA, osteopontin, and lysozyme.
    • Bioactive peptides and glycoprotein glycans contribute to HM's complex functional properties.

    Conclusions:

    • Human milk proteins play a vital role in infant health and development.
    • Understanding HM protein bioactivity can inform the development of enhanced infant formulas.
    • Dairy technology advancements enable the use of bovine milk proteins in clinical studies and commercial products.