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Prescription Infant Formulas Are Contaminated with Aluminium
James Redgrove1, Isabel Rodriguez2, Subramanian Mahadevan-Bava3
1Life Sciences, Huxley Building, Keele University, Staffordshire ST5 5BG, UK. jamesredgrove11@gmail.com.
Insights
Specialized infant formulas show varying aluminum contamination levels, with some nutritional supplements being highly contaminated. This indicates aluminum contamination in infant formulas is not inevitable and can be reduced.
Area of Science:
- Pediatric Nutrition
- Environmental Health
- Analytical Chemistry
Background:
- Off-the-shelf infant formulas are known to be contaminated with aluminum.
- The sources of aluminum contamination in infant formulas are not fully understood.
- Specialized infant formulas cater to specific infant health needs.
Purpose of the Study:
- To measure the aluminum content in specialized prescription infant formulas for the first time.
- To compare aluminum levels in different types of specialized infant formulas.
- To assess the potential for reducing aluminum contamination in infant formulas.
Main Methods:
- Acquired 24 prescription infant formulas from a pediatric clinic.
- Measured total aluminum content using transversely heated graphite furnace atomic absorption spectrometry.
- Utilized microwave-assisted acid/peroxide digestion for sample preparation.
Main Results:
- Ready-to-drink formulas ranged from 49.9 to 1956.3 μg/L in aluminum content.
- Nutritional supplement formulas for infants struggling to gain weight showed the highest contamination.
- Powdered formulas ranged from 0.27 to 3.27 μg/g in aluminum content.
- Formulas for allergies/intolerance tended to be more contaminated among powdered types.
Conclusions:
- Prescription infant formulas are contaminated with aluminum.
- Certain specialized formulas, particularly nutritional supplements, exhibit high aluminum levels.
- The existence of low-aluminum specialized formulas demonstrates that reduced contamination is achievable.
- Manufacturers can mitigate infant aluminum exposure by reducing contamination in specialized infant formulas.
Abstract:
Historical and recent data demonstrate that off-the-shelf infant formulas are heavily contaminated with aluminium. The origin of this contamination remains to be elucidated though may be imported via ingredients, packaging and processing. Specialised infant formulas exist to address health issues, such as low birth weight, allergy or intolerance and medical conditions, such as renal insufficiency. The aluminium content of these prescription infant formulas is measured here for the first time. We obtained 24 prescription infant formulas through a paediatric clinic and measured their total aluminium content by transversely heated graphite furnace atomic absorption spectrometry following microwave assisted acid/peroxide digestion. The aluminium content of ready-to-drink formulas ranged from 49.9 (33.7) to 1956.3 (111.0) μg/L. The most heavily contaminated products were those designed as nutritional supplements for infants struggling to gain weight. The aluminium content of powdered formulas ranged from 0.27 (0.04) to 3.27 (0.19) μg/g. The most heavily contaminated products tended to be those addressing allergies and intolerance. Prescription infant formulas are contaminated with aluminium. Ready-made formulas available as nutritional supplements to aid infant growth contained some of the highest concentrations of aluminium in infant formulas measured in our laboratory. However, a number of prescription infant formulas contained the lowest concentrations of aluminium yet measured in our laboratory. These higher cost specialist preparations demonstrate that the contamination of infant formulas by aluminium is not inevitable. They represent what is achievable should manufacturers wish to address the threat posed to health through infant exposure to aluminium.
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