Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Superior sulcus tumors.

D C Beyer, T Weisenburger

    American Journal of Clinical Oncology
    |April 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Aggressive treatment for superior sulcus tumors, particularly combined irradiation and surgery, improves 5-year survival. Local tumor control is critical for patient survival and preventing spinal cord compression.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Therapeutic Strategies for Localized Prostate Cancer II: Perineal Prostatectomy, X-Rays, Protons, Neutrons, and Combination Brachytherapy.

    Reviews in urology·2006
    Same author

    Prostate brachytherapy: comparison of dose distribution with different 125I source designs.

    Radiology·2001
    Same author

    Pretreatment nomogram for predicting freedom from recurrence after permanent prostate brachytherapy in prostate cancer.

    Urology·2001
    Same author

    The evolving role of prostate brachytherapy.

    Cancer control : journal of the Moffitt Cancer Center·2001
    Same author

    Real-time optimized intraoperative dosimetry for prostate brachytherapy: a pilot study.

    International journal of radiation oncology, biology, physics·2000
    Same author

    Failure free survival following brachytherapy alone for prostate cancer: comparison with external beam radiotherapy.

    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2000

    Area of Science:

    • Thoracic Oncology
    • Radiation Oncology
    • Surgical Oncology

    Background:

    • Superior sulcus tumors are rare but aggressive lung cancers.
    • Treatment outcomes for these tumors historically show limited survival rates.

    Purpose of the Study:

    • To analyze survival outcomes and prognostic factors for patients with superior sulcus tumors.
    • To evaluate the impact of different treatment modalities on survival and failure patterns.

    Main Methods:

    • Retrospective analysis of 35 patients treated between 1960-1983.
    • Evaluation of treatment modalities including megavoltage irradiation and surgical resection.
    • Analysis of prognostic factors such as nodal status, bony erosion, and local tumor control.

    Main Results:

    Related Experiment Videos

    • Combined treatment (irradiation and surgery) yielded a 48% 5-year survival, significantly better than irradiation alone (21%).
    • Local tumor control was strongly associated with survival (71% vs 0% for local recurrence).
    • Local recurrence occurred in 72% of patients, with 39% developing spinal cord compression.

    Conclusions:

    • Superior sulcus tumors are primarily a localized disease requiring aggressive management.
    • Combined modality treatment and achieving local control are crucial for improving survival.
    • While pain relief is achievable, its transient nature highlights the need for durable treatment strategies.