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Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
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Utility of Spatial Point-Pattern Analysis Using Residential and Workplace Geospatial Information to Localize

Jonathan L Chua1, Lee Ching Ng2, Vernon J Lee1

  • 1Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore.

American Journal of Epidemiology
|March 17, 2019
PubMed
Summary
This summary is machine-generated.

A new spatial analysis method accurately pinpoints disease outbreak sources using residential and workplace addresses. This approach aids in faster outbreak control by improving the localization of infection origins.

Keywords:
algorithmsfood-borne diseasesgeographic information systemsinfectious disease outbreakssource localizationsource of outbreakspatial analysisworkplace

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Area of Science:

  • Epidemiology
  • Spatial Analysis
  • Public Health

Background:

  • Effective outbreak control relies on identifying the source.
  • Current spatial methods for outbreak investigation are underutilized due to complexity and performance issues.

Purpose of the Study:

  • To evaluate simple spatial methods for localizing disease outbreak sources.
  • To propose and validate a modified centrographic statistic for improved source localization.

Main Methods:

  • Simulated 30 mock outbreaks to compare 5 parameter-free spatial analysis methods.
  • Utilized residential and workplace addresses to determine outbreak origins.
  • Proposed and tested a 'center of minimum geometric distance with address selection' modification.

Main Results:

  • The proposed method localized mock outbreak sources within a 500 m radius in most cases when using both address types.
  • The method demonstrated good performance even with as few as 10 cases, given sufficient workplace data.
  • Successful application to historical outbreaks, with limitations noted for multisite outbreaks from a single supplier.

Conclusions:

  • A modified spatial analysis method effectively localizes disease outbreak sources.
  • Combining residential and workplace addresses significantly enhances localization accuracy.
  • This approach offers a practical tool for public health officials in outbreak investigations.