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Updated: Jan 27, 2026

Biaxial Mechanical Characterizations of Atrioventricular Heart Valves
Published on: April 9, 2019
A 2:1 atrioventricular block presenting paradoxical ventriculophasic response
Takashi Nakashima1,2, Keita Suzuki2, Takahisa Ido2
1Department of Cardiology, Gifu University School of Medicine Graduate School of Medicine, Gifu, Japan.
Ventriculophasic response (VR), a shortening of sinus cycle length during atrioventricular (AV) block, is typically observed. This case report details a rare instance of both typical and paradoxical VR in a patient with 2:1 AV block.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Arrhythmias
Background:
- Ventriculophasic response (VR) is characterized by a shortened sinus cycle length during atrioventricular (AV) block.
- This phenomenon typically involves shorter PP intervals when a QRS complex intervenes.
Observation:
- An 80-year-old male patient presented with a 2:1 AV block.
- The patient exhibited both typical and paradoxical forms of ventriculophasic response.
Findings:
- The observation of both typical and paradoxical VR in a single patient with 2:1 AV block is a rare clinical finding.
- This case highlights the complex electrophysiological behaviors that can occur with AV conduction abnormalities.
Implications:
- Understanding VR, including its paradoxical form, is crucial for accurate diagnosis and management of complex AV block.
- This case may prompt further investigation into the mechanisms underlying paradoxical VR and its clinical significance.
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