The fight against multidrug-resistant organisms: The role of ZnO crystalline defects
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Updated: Jan 27, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Eva de Lucas-Gil1, Adolfo Del Campo2, Laura Pascual3
1Electroceramic Department, Instituto de Cerámica y Vidrio, CSIC, Kelsen 5, 28049 Madrid, Spain; NanoBioMatters Bactiblock, NanoBioMatters Industries S.L., Louis Pasteur 11, 46980 Paterna, Valencia, Spain.
Abstract:
This article reports the excellent antimicrobial response of nanoparticulate ZnO against multidrug-resistant organisms (MDROs). We demonstrate that the enhanced antimicrobial activity against MDROs depends on the crystalline defects of ZnO. Hence, this work provides insights on the ZnO-microorganism interactions, and we pose combined physico-chemical action mechanisms against resistant bacteria.
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