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Updated: Jan 27, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Copper-Catalyzed Double Thiolation To Access Sulfur-Bridged Imidazopyridines with Isothiocyanate
Lu-Lu Tian1, Shuai Lu1, Zhe-Hua Zhang1
1College of Chemistry and Molecular Engineering , Zhengzhou University , No. 100 of Science Road , Zhengzhou , Henan 450001 , P. R. China.
Abstract:
A copper(I)-catalyzed sulfur-bridged dimerization of imidazopyridines has been developed using isothiocyanate as the sulfur source. This method enables a switchable synthesis of bis(imidazo[1,2- a]pyridin-3-yl)sulfanes or bis(2-(imidazo[1,2- a]pyridin-2-yl)phenyl)sulfanes in the presence of 4-dimethylaminopyridine (DMAP) or K2CO3 when different imidazopyridines were employed. Under optimized conditions, a variety of sulfur-bridged imidazopyridines were obtained in good yields. Moreover, thiourea was proved to be the key intermediate under catalytic system A.
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