Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Alpha-heavy chain disease.

P Haghighi, P L Wolf

Clinics in Laboratory Medicine

|September 1, 1986

Summary

This summary is machine-generated.

Alpha-heavy chain disease (AHCD) involves specific histopathology and lesions. Modern immunohistochemical findings offer insights into its histogenesis, with increasing reports of Burkitt

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Examining the association between socioeconomic status, clinical assessment, and dental caries experience in oncology patients: a 5-year review of a tertiary-care hospital.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2026

Same author

The influence of preformed metal crowns versus zirconia crowns on the diagnostic quality of magnetic resonance images.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2024

Same author

Biochemical diagnosis of liver disease.

Indian journal of clinical biochemistry : IJCB·2012

Same author

Observations on the origin of lymphocyte-like cells in mouse bone marrow.

Nature·2010

Same author

Comparative analyses of multi-species sequences from targeted genomic regions.

Nature·2003

Same author

Elbow synovial fold syndrome: MR imaging findings.

AJR. American journal of roentgenology·2001

Same journal

Advances in Hemostasis Laboratory Testing.

Clinics in laboratory medicine·2026

Same journal

Extracellular Vesicles in Hemostasis.

Clinics in laboratory medicine·2026

Same journal

Thrombin Generation Assay: Ready for Prime Time.

Clinics in laboratory medicine·2026

Same journal

Viscoelastic Testing for the Laboratorian: Recent Advances and Practical Advice.

Clinics in laboratory medicine·2026

Same journal

Practical Recommendations for Harmonization of Hemostasis Testing Across Hospital Sites.

Clinics in laboratory medicine·2026

Same journal

The Role of Hypoxia in Vascular Endothelial Dysfunction and Venous Thromboembolism.

Clinics in laboratory medicine·2026

See all related articles

Area of Science:

Immunopathology
Gastrointestinal Pathology
Pediatric Oncology

Background:

Alpha-heavy chain disease (AHCD) is a rare lymphoproliferative disorder.
Understanding its histopathology and associated lesions is crucial for diagnosis.
Recent immunohistochemical studies provide new insights into its origins.

Purpose of the Study:

To review the histopathology and lesions associated with AHCD.
To discuss unusual clinicopathologic presentations of AHCD.
To explore modern concepts of AHCD histogenesis using immunohistochemical data.

Main Methods:

Review of existing literature on AHCD.
Analysis of histopathological findings.
Discussion of immunohistochemical data and clinicopathologic presentations.

Related Experiment Videos

Main Results:

Detailed description of AHCD histopathology and associated lesions.
Highlighting of unusual clinical and pathological presentations.
Integration of immunohistochemical findings to explain histogenesis.

Conclusions:

AHCD presents with distinct histopathological features.
Immunohistochemistry aids in understanding AHCD's development.
An increase in Burkitt's lymphoma cases in the ileocecal region of children is observed.