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Updated: Jan 27, 2026

Lipidomics and Transcriptomics in Neurological Diseases
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Tutorial on lipidomics.

Jianing Wang1, Chunyan Wang1, Xianlin Han2

  • 1Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.

Analytica Chimica Acta
|March 31, 2019
PubMed
Summary
This summary is machine-generated.

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This tutorial introduces lipidomics, the study of lipids in biological systems using mass spectrometry. It provides essential knowledge and key approaches for researchers new to this expanding field.

Area of Science:

  • Biochemistry
  • Analytical Chemistry
  • Systems Biology

Background:

  • Lipidomics is a rapidly growing field focused on the comprehensive study of lipids.
  • Understanding lipid profiles is crucial for deciphering biological processes and disease mechanisms.
  • An increasing number of researchers require accessible introductions to lipidomic technologies.

Purpose of the Study:

  • To provide a foundational understanding of lipidomics for newcomers.
  • To outline core concepts and essential methodologies in the field.
  • To facilitate the adoption of lipidomic approaches across diverse scientific disciplines.

Main Methods:

  • Mass spectrometry-based techniques are central to lipidomic analysis.
  • Systematic and large-scale studies are employed to capture comprehensive lipid profiles.
Keywords:
LipidomicsLipidsMass spectrometryMetabolic syndromeNeurodegenerative diseasesShotgun lipidomics

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  • Analysis encompasses lipid structure, composition, and quantity in biological samples.

    • Main Results:

    • This tutorial offers a structured overview of lipidomics.
    • Key principles and practical approaches are detailed.
    • The content is designed for researchers entering the field.

    Conclusions:

    • Lipidomics is an essential tool for biological and medical research.
    • This tutorial serves as a guide for researchers new to lipidomics.
    • Mastering lipidomic approaches enhances the understanding of biological systems.