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Published on: September 9, 2020
Phosphaturic Mesenchymal Tumors Involving Skull Bones: Report of Two Rare Cases
Toshi Mishra1, Maria Alina Desouza1, Keyuri Patel1
1Department of Histopathology, Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India.
Abstract:
Phosphaturic mesenchymal tumor (PMT) is a rare tumor causing oncogenic osteomalacia (OO). Most such tumors occur in soft tissue and bones of extremities and appendicular skeleton. Intracranial location and involvement of temporal-occipital bone is extremely rare. We report two unusual cases: The first was intracranial, involving the temporal bone, while the other was a skull base tumor arising from the occipital-temporal bone. Both of them presented with paraneoplastic syndrome of OO, resembled a meningioma radiologically, and underwent gross total resection of tumor. Histologically, both of them were diagnosed as PMT, mixed connective tissue variant.
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