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Association between abdominal obesity and asthma: a meta-analysis
Di Jiang1, Liwen Wang1, Chenxiao Bai1
1School of Nursing, Shandong University, 44 West Wenhua Road, Jinan, Shandong China.
Summary
This meta-analysis confirms a positive link between abdominal obesity and asthma, with a higher risk observed in both males and females. The findings suggest a dose-response relationship, highlighting the importance of managing abdominal weight.
Area of Science:
- Public Health
- Epidemiology
- Respiratory Medicine
Background:
- Conflicting results exist regarding the association between abdominal obesity and asthma.
- The relationship between abdominal obesity and asthma requires further quantitative investigation.
Purpose of the Study:
- To quantitatively determine the association between abdominal obesity and asthma.
- To explore potential dose-response relationships and subgroup variations in this association.
Main Methods:
- A comprehensive meta-analysis was conducted using data from multiple databases up to February 2018.
- Included studies comprised case-control, cohort, and cross-sectional designs.
- Publication bias was assessed using Begg's and Egger's tests.
Main Results:
- A positive association between abdominal obesity and asthma was observed (OR = 1.47, 95% CI 1.35-1.59).
- Consistent positive associations were found across different study designs and age groups.
- Similar associations were noted in both males and females, with a dose-response relationship evident.
Conclusions:
- Abdominal obesity is positively associated with asthma, irrespective of sex.
- A dose-response relationship exists between abdominal weight status and asthma.
- Addressing abdominal obesity is crucial for asthma prevention and management.
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