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Research Output and Global Trends in Lassa Fever: A 50-Year Bibliometric Analysis (1975-2025)
Ifeanyi Ferdinand Chukwuma1, Chioma Miracle Ojiako2,3, Simon Pierre Yinyang Danga4
1Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria, unizik.edu.ng.
Biomed Research International
|August 12, 2026
Summary
This bibliometric study reveals a global increase in Lassa fever research, with the US and Nigeria leading. However, African research output remains low, necessitating greater investment for Lassa fever prevention and control.
Area of Science:
- Medical Research
- Public Health
- Epidemiology
Background:
- Lassa fever is a significant public health threat concentrated in West Africa.
- Bibliometric analysis is crucial for understanding research trends and global contributions.
- Documenting research outputs aids in identifying research gaps and future directions.
Purpose of the Study:
- To conduct a bibliometric analysis of Lassa fever research outputs from 1975 to 2025.
- To identify trends in publication, country participation, institutions, funding, research fields, journals, authors, and keywords.
- To assess global research collaboration and productivity in Lassa fever.
Main Methods:
- Publications on Lassa fever were retrieved from Scopus and Web of Science (WoS) databases.
- Keywords included "Lassa fever," "Lassa virus," "Lassa hemorrhagic fever," "Lassa mammarenavirus," and "LASV."
- Bibliometric analysis was performed using Biblioshiny and VOSviewer for data analysis and network visualization.
Main Results:
- A total of 1776 (Scopus) and 2451 (WoS) English-language original research articles were analyzed.
- Research output increased significantly, peaking in 2024, with the United States and Nigeria as top contributors.
- African countries, despite endemicity, showed limited representation among top global research contributors.
Conclusions:
- The study provides a comprehensive historical perspective on Lassa fever research progress.
- Diverse stakeholders play a pivotal role in advancing Lassa fever research.
- There is a critical need for increased funding and focus on Lassa fever research in Africa to improve prevention and control efforts.