Related Experiment Video

Updated: Jan 26, 2026

Frailty Assessment in an Aging Mouse Model
06:58

Frailty Assessment in an Aging Mouse Model

Published on: September 23, 2025

505

Commentary on Some Recent Theses Relevant to Combating Aging: April 2019

Benjamin Zealley, Aubrey D N J de Grey

    Rejuvenation Research
    |April 9, 2019
    PubMed

    Keywords:
    agingdissertationstheses

    More Related Videos

    Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans11:57

    Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans

    Published on: November 26, 2017

    9.1K
    Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast10:41

    Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast

    Published on: August 20, 2013

    13.3K

    Related Concept Videos

    SI Units: 2019 Redefinition01:13

    SI Units: 2019 Redefinition

    Measurement is an indispensable part of analytical chemistry. The result of measurement helps quantify a substance's physical property and compare it with the physical property of another substance. Each measurement comprises two components - a number indicating the magnitude and a unit of measurement as a standard for comparison. Further, the same quantity can be measured using different units of measurement, which leads to differences in magnitude.
    A standard set of units has been defined...
    3.4K
    Aging01:26

    Aging

    Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
    Cellular Clock Theory
    The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
    659
    The Effect of Aging on Tissues01:19

    The Effect of Aging on Tissues

    Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
    3.4K
    Changes in the Appendicular Skeleton with Age01:09

    Changes in the Appendicular Skeleton with Age

    The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
    Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
    3.4K
    Clinically Relevant Drug Product Specifications: Methods of Establishment01:29

    Clinically Relevant Drug Product Specifications: Methods of Establishment

    Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...
    211
    Pharmacodynamics in Geriatric Patients: Effects of Age01:27

    Pharmacodynamics in Geriatric Patients: Effects of Age

    Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
    193