LAPAROSCOPIC NISSEN ROSETTI FUNDOPLICATION IN TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE: EVALUATION OF LONG TERM...

Area of Science:

• Gastroenterology
• Surgical Innovation
• Patient Outcomes Research

Background:

• Chronic gastroesophageal reflux disease (GERD) significantly impacts patient quality of life.
• Surgical interventions are considered for refractory GERD cases.
• Laparoscopic Nissen Rossetti fundoplication (LNRF) is a surgical option for GERD management.

Purpose of the Study:

• To evaluate the long-term outcomes of LNRF surgery for chronic GERD.
• To assess both objective measures and quality of life improvements post-surgery.
• To compare preoperative and postoperative patient symptomology and reflux severity.

Main Methods:

• A cohort of 32 patients with chronic GERD undergoing LNRF were evaluated.
• Long-term follow-up included subjective symptom assessment and the Gastroesophageal Reflux-Health related Quality of Life index.
• Objective assessment involved 24-hour esophageal pH monitoring before and after surgery.

Main Results:

• Significant improvements in quality of life scores were observed post-LNRF (p=0.001).
• A significant decrease in DeMeester scores, indicating reduced pathological reflux, was noted (p=0.001).
• Postoperative dysphagia was common long-term but did not significantly affect quality of life.

Conclusions:

• Laparoscopic Nissen Rossetti fundoplication is an effective and successful treatment for chronic GERD.
• The procedure leads to long-term prevention of pathological reflux and symptom relief.
• LNRF demonstrably improves patient quality of life in the long term.