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Updated: Jan 26, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
Photo-Crosslinked Keratin/Chitosan Membranes as Potential Wound Dressing Materials
Che-Wei Lin1,2, Yi-Kai Chen3, Min Lu4
1Institute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan. d01642002@ntu.edu.tw.
Abstract:
In this study, we combined two kinds of natural polymers, chitosan and keratin, to develop a portable composite membrane via UV irradiation. UV-crosslinking without an additional chemical agent makes the fabrication more ideal by reducing reactants and avoiding residual toxic chemicals. This novel composite could perform synergistic functions benefitting from chitosan and keratin; including a strong mechanical strength, biodegradability, biocompatibility, better cell adhesion, and proliferation characteristics. Furthermore, compared with our previous research, this keratin-chitosan composite membrane was improved in that it was made to be portable, enabling it to be versatile and have various applications in vitro and in vivo. Based on these facts, this innovative composite membrane has high potential for serving as an outstanding candidate for wound healing or other biomedical applications.
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