Factors associated with pseudoaneurysm development and necessity for reintervention: a single centre study

Area of Science:

• Vascular Surgery
• Interventional Radiology
• Medical Devices

Background:

• Peripheral pseudoaneurysms are a potential complication of endovascular procedures.
• Treatment options include ultrasound-guided thrombin injection (UGTI) and surgical repair.
• Understanding factors influencing treatment outcomes and reintervention is crucial.

Purpose of the Study:

• To evaluate factors associated with pseudoaneurysm development and morphology.
• To compare outcomes of UGTI and surgical treatment for pseudoaneurysms.
• To determine the necessity for post-intervention reintervention.

Main Methods:

• Retrospective analysis of ultrasound scans and CT angiography from February 2011 to April 2017.
• Inclusion of 99 patients undergoing peripheral pseudoaneurysm interventions.
• Multivariate analysis of patient demographics, including anticoagulant and antiplatelet medication.

Main Results:

• Primary intervention success rates were high for both UGTI (98.9%) and surgery (100%).
• Reintervention risk factors included pre-intervention thrombocytopenia (p=0.025) and pseudoaneurysms post-vascular surgery (p=0.033).
• Warfarinized patients developed larger pseudoaneurysm sacs compared to other regimens.

Conclusions:

• Pre-intervention thrombocytopenia and pseudoaneurysms following vascular surgery are key risk factors for reintervention.
• Patients on warfarin developed larger pseudoaneurysm sacs.
• Post-intervention imaging surveillance may benefit high-risk subgroups.