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Adult intussusception: a systematic review and meta-analysis
1Department of Colorectal Surgery, Korea University Ansan Hospital, Gyeonggi-Do, Republic of Korea.
Optimal surgical treatment for adult intussusception varies by location. Enteric intussusception may involve reduction and resection, while colonic intussusception requires en bloc resection to prevent tumor spread.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Abdominal Surgery
Background:
- Adult intussusception is rare, leading to controversial optimal treatment strategies.
- Determining the appropriate surgical procedure for adult intussusception is crucial.
Purpose of the Study:
- To determine the appropriate surgical procedure for adult intussusception.
- To analyze the etiology, location, and outcomes of adult intussusception.
Main Methods:
- Systematic literature search of PubMed, Embase, and Web of Science (1980-2016).
- Inclusion of adult patients (>15 years) with intussusception treated surgically or conservatively.
- Analysis of pooled data from 40 retrospective case series involving 1229 patients.
Main Results:
- Malignant tumors (32.9%), benign tumors (37.4%), and idiopathic causes (15.1%) were identified.
- Enteric (49.5%), ileocolic (29.1%), and colonic (19.9%) were the main locations.
- Malignancy rates were higher in colonic (46.5%) and ileocolic (36.9%) intussusception compared to enteric (22.5%).
- En bloc resection without reduction is recommended for colonic intussusception due to high malignancy rates.
- Postoperative complications and mortality rates were 22.1% and 5.2%, respectively.
Conclusions:
- Enteric intussusception management: reduction followed by resection.
- Colonic intussusception management: en bloc resection without reduction.
- A selective approach is recommended due to intermediate forms.
- Surgery remains the primary treatment for adult intussusception.
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