Dataset of growth cone-enriched lipidome and proteome of embryonic to early postnatal mouse brain
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Updated: Jan 25, 2026

In Situ Visualization of Axon Growth and Growth Cone Dynamics in Acute Ex Vivo Embryonic Brain Slice Cultures
Published on: October 14, 2021
Anna Trzeciecka1, Sanjoy K Bhattacharya1
1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, FL 33136, USA.
Abstract:
A growth cone is a part of a neuron considered as a hub for axon growth, motility and guidance functions. Growth cones are thought to play a critical role during development of neurons. Growth cones also play a significant role in adult regeneration. Here, we present a dataset on the lipid and protein profiling of the growth cone-enriched fractions derived from C57BL/6J mice forebrains of developmental stage: E18, P0, P3, P6, and P9. For comparison, we analyzed non-growth cone membranes from the same samples. Lipid data is available at the Metabolomics Workbench [http://www.metabolomicsworkbench.org (Project ID: PR000746)]. Protein data is available at Proteomics Identifications (PRIDE) partner repository (PRIDE identifier PXD012134).
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