Strain Release of Donor-Acceptor Cyclopropyl Boronate Complexes
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Updated: Jan 25, 2026

Negative Additive Manufacturing of Complex Shaped Boron Carbides
Published on: September 18, 2018
Charlotte H U Gregson1, Venkataraman Ganesh1, Varinder K Aggarwal1
1School of Chemistry , University of Bristol , Cantock's Close, Bristol BS8 1TS , U.K.
Abstract:
The reactivity of boronate complexes which resemble donor-acceptor cyclopropanes is described. The enantioenriched cyclopropyl boronate complexes were shown to undergo concerted 1,2-metalate rearrangement/ring opening upon activation with a Lewis acid. This method provides atom-efficient access to optically active γ-carbonyl boronic esters in moderate to excellent yields with complete enantiospecificity. Furthermore, a three-component variant of the reaction was established through in situ alkylation, and the synthetic utility of the products as chiral building blocks was demonstrated.
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