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Updated: Jan 25, 2026

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring
Published on: June 13, 2025
Approach Angle Affects Accuracy in Robotic Stereoelectroencephalography Lead Placement.
Jordan C Iordanou1, Divaldo Camara1, Saadi Ghatan1
1Department of Neurosurgery, Mount Sinai West, New York, New York, USA.
Planning robotic epilepsy surgery trajectories with high skew angles (>30°) increases placement error. Surgeons should minimize steep angles or use larger safety margins for accurate electrode placement in stereoelectroencephalography.
Area of Science:
- Neurosurgery
- Robotic Surgery
- Epilepsy Research
Background:
- Epilepsy affects many patients unresponsive to medication, necessitating advanced surgical options.
- Stereoelectroencephalography (SEEG) with depth electrodes is crucial for mapping epileptogenic networks.
- Robotic systems like ROSA offer improved efficiency and comparable accuracy in electrode placement compared to traditional methods.
Purpose of the Study:
- To investigate the impact of planned trajectory angle on the accuracy of robotic-assisted SEEG electrode placement.
- To identify factors influencing electrode deviation during stereotactic neurosurgery.
Main Methods:
- Analysis of 319 SEEG trajectories from 25 patients using ROSA robotic system.
- Computation of skew angle and accuracy using fused preoperative/postoperative CT scans and planned trajectories.
- Comparison of placement accuracy between oblique (>30°) and orthogonal (<30°) trajectory angles.
Main Results:
- Oblique trajectories (>30° skew angle) showed significantly higher radial error (2.05 mm) compared to orthogonal trajectories (<30° skew angle; 1.45 mm).
- The difference in radial error was statistically significant (P < 0.001).
Conclusions:
- ROSA robotic system enhances speed and efficiency in stereotactic neurosurgery.
- Minimizing high skew angles in trajectory planning is critical for accurate electrode placement.
- When high skew angles are unavoidable, increased safety margins are recommended to mitigate placement errors.
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