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Sucrose octaacetate.

William Craig Stagner1, Shalini Gaddam2, Rudrangi Parmar1

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Summary
This summary is machine-generated.

Sucrose octaacetate (SOA) is a nontoxic, bitter-tasting natural product used as a compendial material. Its low molar absorptivity and potential for numerous isomers are key characteristics.

Keywords:
Bitter tasting adjuvantSaccharose octaacetateSucrose octaacetate

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Area of Science:

  • Natural Products Chemistry
  • Pharmacognosy
  • Analytical Chemistry

Background:

  • Sucrose octaacetate (SOA) is a compendial material listed in the United States National Formulary.
  • It is a naturally occurring compound extracted from Annona cornifolia seeds.
  • SOA possesses a distinct bitter taste, leading to its application as a repellent.

Purpose of the Study:

  • To characterize Sucrose octaacetate (SOA).
  • To detail its properties and potential applications.

Main Methods:

  • Literature review of existing data on SOA.
  • Analysis of its chemical structure and properties.

Main Results:

  • SOA is a sucrose derivative with eight acetate groups.
  • It is non-toxic and exhibits a very low molar absorptivity.
  • SOA can form 255 different isomers and degradation products.
  • Reported ultraviolet molar absorptivity at 210nm is 439 units/cm/M in water and 442 units/cm/M in 30:70 acetonitrile-water.

Conclusions:

  • Sucrose octaacetate is a well-characterized natural product with specific physicochemical properties.
  • Its bitter taste and low molar absorptivity are notable features for potential applications.