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Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
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An Analysis of Popular Online Erectile Dysfunction Supplements
Adithya Balasubramanian1, Nannan Thirumavalavan2, Ashwin Srivatsav1
1Baylor College of Medicine, Houston, TX, USA.
The Journal of Sexual Medicine
|May 1, 2019
Summary
Efficacy of popular online erectile dysfunction supplements (ED-Ss) is questionable, with limited human studies and many disingenuous reviews. Patients should seek FDA-approved therapies and counseling.
Area of Science:
- Integrative medicine
- Pharmacology
- Consumer health
Background:
- Erectile dysfunction supplements (ED-Ss) are widely marketed online with claims of natural efficacy.
- The actual effectiveness and safety of these supplements remain largely unverified.
- Limited data hinders effective patient counseling on ED-S use.
Purpose of the Study:
- To evaluate top-rated and frequently reviewed ED-Ss on Amazon.com.
- To analyze ingredient profiles and assess evidence for efficacy and safety.
- To provide data for informed patient counseling regarding ED-Ss.
Main Methods:
- Searched Amazon.com for "erectile dysfunction" and reviewed the top 6 ED-Ss.
- Analyzed product details including price, ratings, reviews, manufacturer, and ingredients.
- Filtered consumer reviews using ReviewMeta.com to assess International Index of Erectile Function (IIEF) scores.
Main Results:
- Top ED-Ss contained popular ingredients like ginseng and L-arginine, with limited supporting human studies (12/69).
- Post-review filtration showed significant decreases in reported improvements for erection strength (77%), sexual satisfaction (90%), and confidence (89%).
- Analysis revealed a substantial reduction in positive user experiences after filtering potentially untrustworthy reviews.
Conclusions:
- Human studies on ED-S ingredients show limited and inconclusive efficacy for erectile dysfunction.
- The prevalence of misleading reviews necessitates caution and professional guidance for patients.
- Food and Drug Administration-approved therapies are recommended over unverified ED-Ss.
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