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Localized subepidermal bullae after intravenous phenobarbital
Cutis
|March 1, 1987
Summary
Barbiturate-induced coma can cause skin blisters and sweat gland damage. A patient developed blisters without sweat gland necrosis near an IV site, suggesting a potential alternative mechanism for barbiturate-induced bulla formation.
Area of Science:
- Dermatology
- Neurology
- Pharmacology
Background:
- Subepidermal bullae and sweat gland necrosis are known complications of barbiturate-induced coma.
- Barbiturates are central nervous system depressants used for sedation and seizure control.