Takayasu arteritis with multiple coronary involvement and early graft relapse

Area of Science:

• Cardiovascular Medicine
• Rheumatology
• Vascular Inflammation

Background:

• Takayasu arteritis (TA) is a rare large-vessel vasculitis.
• Coronary artery disease (CAD) is an uncommon manifestation of TA.
• This case highlights the challenges in managing TA-associated complex CAD.

Observation:

• A young woman presented with severe, multi-vessel CAD attributed to Takayasu arteritis.
• Initial treatment involved coronary artery bypass grafting (CABG).
• Early venous graft stenosis occurred despite immunosuppressive therapy.

Findings:

• Recurrent graft stenosis necessitated intervention.
• Drug-eluting stent placement led to symptom resolution.
• Successful management required a multi-faceted approach.

Implications:

• This case underscores the intricate diagnostic and therapeutic pathways for TA with complex CAD.
• Early recognition and aggressive management are crucial for favorable outcomes.
• Further research into optimal treatment strategies for TA-related CAD is warranted.