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Updated: Jan 25, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
Real-Time Volumetric Imaging of Vitreoretinal Surgery with a Prototype Microscope-Integrated Swept-Source OCT Device
Michael I Seider1, Oscar M Carrasco-Zevallos2, Randall Gunther3
1Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina; Department of Ophthalmology, The Permanente Medical Group, San Francisco, California; Department of Ophthalmology, University of California, San Francisco, California.
This study shows that microscope-integrated swept-source optical coherence tomography (SS-OCT) provides high-quality, near-real-time 3D images during macular surgery. This advanced imaging helps surgeons visualize delicate maneuvers and retinal changes during procedures.
Area of Science:
- Ophthalmology
- Medical Imaging
- Surgical Technology
Background:
- Intraoperative imaging is crucial for guiding complex ophthalmic surgeries.
- Near-real-time visualization of surgical maneuvers can improve outcomes in vitreoretinal procedures.
Purpose of the Study:
- To evaluate the utility and image quality of intraoperative near-real-time volumetric swept-source (SS) OCT during macular surgery.
- To assess the ability of SS-OCT to visualize surgical instruments and tissue deformation during vitreoretinal procedures.
Main Methods:
- A prospective translational study involving 41 adult patients undergoing vitreoretinal surgery.
- A novel microscope-integrated SS-OCT prototype captured volumetric images in near-real-time.
- Images were displayed to the surgeon via a heads-up display and formally analyzed postoperatively.
Main Results:
- Volumetric SS-OCT images were deemed acceptable in 92% of patients.
- Successful volumetric imaging of scraping and peeling procedures was achieved in 75% and 78% of cases, respectively.
- The system provided near-real-time volumetric visualization of instruments, retinal surface, and deformation.
Conclusions:
- The microscope-integrated SS-OCT prototype offers high-detail, near-real-time volumetric imaging capabilities.
- This technology shows promise for enhancing surgical precision during delicate macular procedures.
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