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Updated: Jan 25, 2026

A Unified Methodological Framework for Vestibular Schwannoma Research
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Vestibular Schwanomma: An Experience in a Developing World.

Prakash Bahadur Thapa1, Sudha Shahi1, Rajiv Kumar Jha2

  • 1Department of Otorhinolaryngology Head and Neck Surgery, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

World Journal of Oncology
|May 10, 2019
PubMed
Summary

Vestibular schwannoma, a common cerebellopontine angle tumor, presents with hearing loss. Surgery is effective, preserving facial function, but hearing rarely improves post-operatively.

Keywords:
Hearing lossManagementNeuromaVestibular schwannoma

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Area of Science:

  • Neurosurgery
  • Oncology
  • Audiology

Background:

  • Vestibular schwannomas (acoustic neuromas) are benign, slow-growing tumors originating from Schwann cells, accounting for 90% of cerebellopontine angle diseases.
  • Surgical intervention is the primary treatment, though conservative
  • wait and watch
  • approaches are sometimes considered.
  • Understanding clinical presentation and perioperative outcomes is crucial for effective management.

Purpose of the Study:

  • To analyze the clinical presentation of vestibular schwannoma.
  • To evaluate the management strategies and surgical outcomes.
  • To assess perioperative results in a Nepalese patient cohort.

Main Methods:

  • A retrospective review of 33 patients with vestibular schwannoma who underwent surgery between January 2014 and January 2017.
  • Analysis of demographic data, clinical presentation, and perioperative outcomes.
  • Focus on surgical approach, tumor grade, and functional preservation.

Main Results:

  • Hearing loss was the predominant symptom (72%), followed by tinnitus and dizziness.
  • The mean tumor size was 39.7 mm, with a mean patient age of 46 years; female patients showed a slight preponderance (1.2:1).
  • The retrosigmoid approach was favored, achieving 93% facial nerve function preservation. Postoperative hearing improvement was rare (6%), with no significant correlation found between outcomes and tumor characteristics (size, age, gender, laterality). No perioperative mortality occurred.

Conclusions:

  • Early diagnosis and treatment of vestibular schwannoma are challenging, particularly in resource-limited settings.
  • This study provides valuable insights into the disease's incidence and management in Nepal.
  • Further research is essential to enhance understanding and improve patient care for vestibular schwannoma.