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Related Experiment Video

Updated: Jan 25, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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[Psoriasis and the microbiome].

M Witte1, D Thaçi2

  • 1Klinik für Dermatologie, UKSH Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland. mareike.witte@uksh.de.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|May 12, 2019
PubMed
Summary
This summary is machine-generated.

Changes in the skin and gut microbiome are linked to psoriasis development and progression. Analyzing the microbiome may help predict treatment responses in psoriasis patients.

Keywords:
Anti-infective agentsBiomarkersHigh-throughput nucleotide sequencingMicrobiomeMicrobiota

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Area of Science:

  • Dermatology
  • Immunology
  • Microbiome research

Background:

  • Psoriasis is a common chronic inflammatory disease with systemic effects.
  • Alterations in the microbiome are implicated in psoriasis onset and disease course.

Purpose of the Study:

  • To describe current methods for detecting microbiome changes.
  • To explore the role of the microbiome in psoriasis pathogenesis.

Main Methods:

  • Conducted a literature search using Medline and PubMed.
  • Included general internet and book research.

Main Results:

  • Both skin and gut microbiota influence psoriasis immunopathogenesis.
  • Antimicrobial peptides link microbiome and immune mechanisms in psoriasis.
  • 16S rRNA next-generation sequencing advances microbiome analysis.

Conclusions:

  • Microbiome analysis in psoriasis patients can identify biomarkers.
  • Biomarkers may predict individual treatment responses.
  • Microbiome data can guide treatment decisions for psoriasis.