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Intravital Video Microscopy Measurements of Retinal Blood Flow in Mice
Published on: December 26, 2013
Choriocapillary Blood Flow in Myopic Subjects Measured With OCT Angiography
Background And Objective:
To investigate choriocapillary blood flow in myopic eyes using optical coherence tomography angiography.
Patients And Methods:
Seventy-eight myopic and 79 age-matched healthy eyes were included in this study, with myopia defined as a spherical equivalent refraction (SER) between -1 diopters (D) and -6 D. Quantitative measurements of the choriocapillaris were obtained using the Avanti RTVue XR with AngioVue. Choroidal thickness (CT) was assessed using the single-line enhanced high-definition scan of the same device.
Results:
CT correlated positively with SER (P = .017) and negatively with bulbus axial length (AL) (P = .180). Subfoveal choriocapillary blood flow did not show any significant correlation with any of the parameters SER, AL, or CT (P = .798, P = .269, and P = .820, respectively). The mean flow signal of the myopic group did not differ significantly from the mean flow signal of the emmetropic control group (P = .266).
Conclusion:
Choriocapillary blood flow seems to retain a constant level with increasing physiological myopia. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e133-e139.].
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