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Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
CLINICAL AND BIOCHEMICAL MARKERS IN THE DIAGNOSIS OF BACTERIAL ARTHRITIS OF KNEE JOINT AND PERIPROSTHETIC INFECTION
D Morozenko1, O Marushak2, K Gliebova3
11National University of Pharmacy, Kharkiv; 2Sytenko Institute of Spine and Joint Pathology, Kharkiv, Ukraine.
Abstract:
Based on the results of hematological, biochemical, immunological, clinical microscopic and bacteriological studies, the article assessed the condition of patients with bacterial arthritis of the knee joints and periprosthetic infection of the hip joints and developed an algorithm for their clinical and laboratory examination. The algorithm clinical-laboratory examination of patients based on the most informative laboratory markers for bacterial arthritis of the knee: number of stab neutrophils, erythrocyte sedimentation rate, glycoproteins, haptoglobin (the exponents of the inflammatory process), chondroitinsulfates (markers destruction of cartilage and bone of the affected joints) circulating immune complexes (an indicator of the reactivity of the immune system to the toxic-infectious inflammatory process), cytosis, neutrophils and synoviocytes (markers of articular punctate and the nature of the inflammatory process).
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