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Updated: Jan 24, 2026

Laparoscopic Anatomical Hepatectomy Using Takasaki's Approach and Indocyanine Green Fluorescence Navigation
Published on: May 16, 2025
Laparoscopic Repeat Hepatectomy with Indocyanine Green Fluorescence Navigation: A Case Report
Masato Yoshioka1, Nobuhiko Taniai2, Youichi Kawano3
1Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School Hospital.
Indocyanine green (ICG) fluorescence navigation aids laparoscopic hepatectomy for liver cancer recurrence. This method enhances tumor visualization during surgery, improving outcomes for patients with complex surgical histories.
Area of Science:
- Hepatobiliary surgery
- Surgical oncology
- Minimally invasive surgery
Background:
- Hepatocellular carcinoma (HCC) recurrence necessitates surgical intervention, often complicated by previous abdominal surgeries.
- Laparitic hepatectomy (LRH) offers benefits but requires precise tumor localization, especially in cases of recurrent disease.
- Indocyanine green (ICG) fluorescence has shown promise for intraoperative tumor visualization in liver cancer.
Observation:
- A 73-year-old male with a history of multiple laparotomies for HCC presented with liver recurrence.
- Laparoscopic repeat hepatectomy (LRH) was planned using an ICG fluorescence navigation system.
- ICG dye was administered intravenously two days prior to the surgical procedure.
Findings:
- Intraoperative ICG fluorescence provided clear visualization of the recurrent HCC in the lateral liver segment.
- The ICG fluorescence navigation system facilitated precise tumor identification and resection during laparoscopic surgery.
- Laparoscopic partial liver resection (S3) was successfully completed with a short operation time (197 minutes) and minimal blood loss (30 mL).
Implications:
- ICG fluorescence navigation is a valuable tool for enhancing intraoperative visualization in laparoscopic hepatectomy for recurrent liver cancer.
- This technique can improve surgical precision and potentially reduce complications in patients with challenging surgical histories.
- The successful application of ICG fluorescence navigation in LRH supports its broader adoption in liver cancer surgery.
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