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Fast and Accurate Exhaled Breath Ammonia Measurement
Published on: June 11, 2014
Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective
Michiel A G E Bannier1, Philippe P R Rosias2, Quirijn Jöbsis1
1Department of Pediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Center, Maastricht, Netherlands.
Abstract:
Exhaled breath condensate (EBC) was introduced more than two decades ago as a novel, non-invasive tool to assess airway inflammation. This review summarizes the latest literature on the various markers in EBC to predict asthma in children. Despite many recommendations and two comprehensive Task Force reports, there is still large heterogeneity in published data. The biggest issue remains a lack of standardization regarding EBC collection, preservation, processing, and analysis. As a result, published studies show mixed or conflicting results, questioning the reproducibility of findings. A joint, multicenter research study is urgently needed to address the necessary methodological standardization.
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