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Ocular Toxoplasmosis Presenting as Subretinal Macrocyst.
Saeed Karimi1,2, Homayoun Nikkhah1,2, Sahba Fekri1,2
1Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Journal of Ophthalmic & Vision Research
|May 23, 2019
Summary
Ocular toxoplasmosis can present atypically as unilateral retinal detachment with a large subretinal cyst. Early diagnosis and treatment are crucial for successful retinal reattachment and vision preservation.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Parasitology
Background:
- Ocular toxoplasmosis is a common cause of infectious posterior uveitis.
- Retinal detachment is a rare but serious complication of ocular toxoplasmosis.
Observation:
- A healthy 30-year-old woman presented with progressive vision loss in one eye.
- Examination revealed total retinal detachment with a large subretinal cyst and retinal scars.
- B-scan echography confirmed a large subretinal cyst with heterogeneous echogenicity.
Findings:
- Surgical removal of the cyst revealed intraretinal Toxoplasma cysts containing bradyzoites.
- Intraocular fluid analysis using PCR and serology supported the diagnosis.
- The patient's retina remained attached with no inflammation six months post-surgery.
Implications:
- Toxoplasma retinochoroiditis should be considered in cases of retinal detachment with subretinal cysts.
- This case highlights an unusual presentation of ocular toxoplasmosis.
- Prompt diagnosis and intervention can lead to favorable visual outcomes.

