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Updated: Jan 24, 2026

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites
Published on: March 22, 2016
Integration of a photocleavable element into DNA nanoswitches
Arun Richard Chandrasekaran1, Jibin Abraham Punnoose1, Vibhav Valsangkar2
1The RNA Institute, University at Albany, State University of New York, Albany, NY 12222, USA. arun@albany.edu khalvorsen@albany.edu.
Abstract:
Reconfigurable DNA nanostructures can be designed to respond to external stimuli such as nucleic acids, pH, small molecules and enzymes. In this study, we incorporated photocleavable linkers in DNA strands that trigger a conformational change in binary DNA nanoswitches. We demonstrate control of the output using UV light, with potential applications in biosensing and molecular computation.
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