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Cystic fibrosis year in review 2018, part 2

Adrienne P Savant1,2,3, Susanna A McColley1,2,3

  • 1Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Pediatric Pulmonology
|May 25, 2019
PubMed

Insights

In 2018, research on cystic fibrosis (CF) highlighted its widespread effects and exacerbations. Studies also explored new therapies and patient-reported outcomes beyond CFTR modulator treatments.

Area of Science:

  • Pulmonology
  • Genetics
  • Clinical Medicine

Background:

  • Cystic Fibrosis (CF) is a genetic disorder affecting multiple organ systems.
  • 2018 saw significant research output concerning CF's complexities.

Purpose of the Study:

  • To summarize key 2018 publications on cystic fibrosis.
  • To cover multisystem effects, pulmonary exacerbations, novel therapies, and patient-reported outcomes.

Main Methods:

  • Literature review of 2018 publications.
  • Categorization of studies based on research focus.

Main Results:

  • Publications detailed the multisystemic impact of CF.
  • Research addressed pulmonary exacerbations and emerging therapeutic strategies.
  • Patient-reported priorities and outcomes were a significant focus.

Conclusions:

  • 2018 research provided a comprehensive overview of CF.
  • Understanding CF requires a focus on systemic effects, exacerbations, diverse therapies, and patient perspectives.

Keywords:
cystic fibrosis (CF)depressionnutritionpulmonary exacerbation

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