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Updated: Jan 24, 2026

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
Published on: December 16, 2022
Diversity-Oriented Synthesis toward Fused and Bridged Benzobicyclic Piperidin(on)es
Tomasz J Idzik1, Zofia M Myk1, Jacek G Sośnicki1
1Faculty of Chemical Technology and Engineering, Department of Organic and Physical Chemistry , West Pomeranian University of Technology , Al. Piastów 42 , Szczecin 71-065 , Poland.
Abstract:
An efficient diverse synthesis of cis-fused indenopiperidines and bridged benzomorphanones, starting from cyclopropane-fused benzomorphanothiones and benzomorphanones, respectively, using NaBH4/NiCl2·6H2O/EtOH as a reducing system, is described. High rigidity of substrates allowed axially controlled syntheses of their trans-mono-alkylated derivatives, subsequently enabling access to both trans-alkyl-functionalized benzobicyclic piperidin(on)es. Diversity-oriented synthesis of naphthalene ring-containing fused naphthoindenopiperidines and bridged naphthomorphanone directly from 2-pyridones was also performed.
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