Axial length development in children
Austin Bach1, Victor M Villegas2, Aaron S Gold3
1Larkin Eye Institute, Miami, Florida 33143, USA.
Insights
Pediatric ocular axial lengths grow most rapidly in the first 10 months of life and stabilize after 36 months in healthy eyes. This data aids in diagnosing pediatric eye conditions.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Biometry
Background:
- Accurate measurement of ocular axial length is crucial for diagnosing and managing various pediatric eye conditions.
- Establishing normative data for axial length in healthy pediatric eyes is essential for comparison.
Purpose of the Study:
- To establish a normative model for ocular axial length in pediatric subjects without intraocular pathology.
- To analyze the pattern of axial length growth in healthy children.
Main Methods:
- Retrospective chart review of axial lengths from 330 eyes of 165 pediatric subjects examined under anesthesia.
- Inclusion criteria: absence of intraocular pathology; exclusion criteria: presence of intraocular pathology.
- Development of an axial length growth model using logarithmic regression, with stratification by age groups.
Main Results:
- The study included 330 eyes from 165 pediatric subjects with a mean age of 30.62 months.
- The steepest increase in ocular axial length was observed during the first 10 months of life.
- No statistically significant axial length growth was detected after 36 months of age.
Conclusions:
- This study provides the largest dataset of pediatric ocular axial lengths in healthy eyes.
- The developed axial length model can aid in the diagnosis and management of pediatric ophthalmic diseases.
- Normative data is critical for identifying deviations from typical growth patterns.
Aim:
To study ocular axial lengths in pediatric subjects without intraocular pathology.
Methods:
An Institutional Review Board-approved consecutive retrospective chart review of axial lengths measured in pediatric subjects who underwent examination under anesthesia due to positive family history of retinoblastoma or other inherited ocular disease. Only subjects without any intraocular pathology in either eye were included. Subjects were stratified into age groups. An axial length model using a logarithmic regression algorithm was calculated.
Results:
Data from 330 eyes of 165 subjects were included in the study. The mean age at the time of examination was 30.62 (SD 18.04)mo. The steepest increase in axial length was present during the first 10mo of life. After 36mo, there was no statistically significant axial length growth.
Conclusion:
This study presents the biggest series of pediatric axial lengths in healthy eyes. The axial length model developed with these data may assist in the diagnosis and management of a wide variety of pediatric ophthalmic diseases.
Related Concept Videos
Axial and Appendicular Muscles
Axial Muscles
Axial muscles, situated along the body's midline, are intricately connected to the axial skeleton, which includes the skull, spine, ribs, and sternum. These muscles facilitate facial expressions and...
General Case of Eccentric Axial Loading
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical...
Overview of the Axial Skeleton
The axial skeleton of the...
Normal Strain under Axial Loading
Fimbriae, Pili, and Axial Filaments
Eccentric Axial Loading in a Plane of Symmetry


