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Equine protozoal myeloencephalitis
The Veterinary Clinics of North America. Equine Practice
|August 1, 1987
Abstract:
Equine protozoal myeloencephalitis (EPM) is a disease that produces neurologic signs of brain or spinal cord dysfunction. The causative organism is believed to be a Sarcocystis species of protozoa. A definitive diagnosis can only be made on histopathology of affected spinal cord or brain. No preventive measures or documented treatment is available at this time for suspected cases of EPM.
Insights
Equine protozoal myeloencephalitis (EPM) is a neurological disease in horses caused by Sarcocystis protozoa. Definitive diagnosis requires histopathology, and currently, no prevention or treatment is available.
Area of Science:
- Veterinary Neurology
- Parasitology
- Equine Medicine
Background:
- Equine protozoal myeloencephalitis (EPM) is a significant neurological disease affecting horses.
- Clinical signs include dysfunction of the brain or spinal cord.
- The disease is caused by protozoa, likely a Sarcocystis species.
Purpose of the Study:
- To summarize the current understanding of Equine protozoal myeloencephalitis (EPM).
- To highlight diagnostic challenges and limitations in equine neurological disease management.
Main Methods:
- Diagnosis relies on definitive histopathological examination of affected central nervous system tissues.
- Clinical and pathological findings are used to characterize the disease.
Main Results:
- EPM presents with diverse neurological deficits.
- Identification of Sarcocystis species as the presumed causative agent.
- Histopathology remains the gold standard for definitive diagnosis.
Conclusions:
- Equine protozoal myeloencephalitis (EPM) is a challenging neurological condition in horses.
- Current limitations include the lack of preventive strategies and documented treatments for EPM.
- Further research is needed to develop effective interventions for this disease.